Physionic

Hi all - I unlisted my LMHR video, because I received some excellent critiques and was made aware of some additional information I wasn't aware of during the first recording. So, I'm going to address those critiques and upload a new video, but I'll include the original video in the description of the new video for those that still want to see what I originally said.

I appreciate the respectful, critical feedback, as always.

1 month ago | [YT] | 1,285

Physionic

After much deliberation with family and friends, I have made the difficult decision...

...to wear a belt.

IYKYK. 😉

2 months ago | [YT] | 435

Physionic

Hi all - I'm doing a promised live session with the Physionic Community this Saturday. I'll be covering my personal research and just generally hanging out. It's free, but you must be part of the free Physionic Community (bit.ly/PhysionicCommunity2) or on the email list (bit.ly/2AXIzK6) to join.

Neither the live session nor the recording will be on YouTube, so be sure to join via either method above, if you can!

Should be a fun time - hope you can make it,
Nic

5 months ago | [YT] | 166

Physionic

C15 Fats. I had to break it into 2 videos, because I had a lot to say. Releases next week (barring any complications with editing).

For reference, I started reading the studies on the topic over 2 weeks ago - it takes a long time to make sure the information is accurate and fair, but I'm very much looking forward to discussing with you - these were fun videos...

See you on Monday (and have a great weekend!),
Nic

8 months ago | [YT] | 751

Physionic

Hi all - I've looked over the literature for studies on canola oil and inflammation (in humans) and found 8 studies (see below). I'm wondering, since seed oils and canola oil are such polarizing topics and *surely* people have presented evidence for their stances, if you know of any other studies (in humans) that look at canola oil/rapeseed oil and inflammation (pro-inflammatory, anti-inflammatory, etc.) that I have missed, could you post them below?

I'd like to review all the studies I can so it doesn't seem like I'm cherry picking. Please post any below - they can be associative, but preferably RCTs (in humans).

Studies I have already:
1. Nikooyeh B, Zargaraan A, Ebrahimof S, et al. Daily consumption of γ-oryzanol-fortified canola oil, compared with unfortified canola and sunflower oils, resulted in a better improvement of certain cardiometabolic biomarkers of adult subjects with type 2 diabetes: a randomized controlled clinical trial. Eur J Med Res. 2023;28(1):416. Published 2023 Oct 10. doi:10.1186/s40001-023-01409-8

2. Morvaridi M, Jafarirad S, Seyedian SS, Alavinejad P, Cheraghian B. The effects of extra virgin olive oil and canola oil on inflammatory markers and gastrointestinal symptoms in patients with ulcerative colitis. Eur J Clin Nutr. 2020;74(6):891-899. doi:10.1038/s41430-019-0549-z

3. Khandouzi N, Zahedmehr A, Nasrollahzadeh J. Effects of canola or olive oil on plasma lipids, lipoprotein-associated phospholipase A2 and inflammatory cytokines in patients referred for coronary angiography. Lipids Health Dis. 2020;19(1):183. Published 2020 Aug 14. doi:10.1186/s12944-020-01362-z

4. Atefi M, Pishdad GR, Faghih S. The effects of canola and olive oils on insulin resistance, inflammation and oxidative stress in women with type 2 diabetes: a randomized and controlled trial. J Diabetes Metab Disord. 2018;17(2):85-91. Published 2018 May 23. doi:10.1007/s40200-018-0343-9

5. Manning PJ, Sutherland WH, McGrath MM, de Jong SA, Walker RJ, Williams MJ. Postprandial cytokine concentrations and meal composition in obese and lean women. Obesity (Silver Spring). 2008;16(9):2046-2052. doi:10.1038/oby.2008.334

6. Gillingham LG, Gustafson JA, Han SY, Jassal DS, Jones PJ. High-oleic rapeseed (canola) and flaxseed oils modulate serum lipids and inflammatory biomarkers in hypercholesterolaemic subjects. Br J Nutr. 2011;105(3):417-427. doi:10.1017/S0007114510003697

7. Liu X, Kris-Etherton PM, West SG, et al. Effects of canola and high-oleic-acid canola oils on abdominal fat mass in individuals with central obesity. Obesity (Silver Spring). 2016;24(11):2261-2268. doi:10.1002/oby.21584

8. Perez-Herrera A, Delgado-Lista J, Torres-Sanchez LA, et al. The postprandial inflammatory response after ingestion of heated oils in obese persons is reduced by the presence of phenol compounds. Mol Nutr Food Res. 2012;56(3):510-514. doi:10.1002/mnfr.201100533

(Human studies only, did I mention that already? :) )

Thanks!

8 months ago (edited) | [YT] | 864

Physionic

Video take-down:
Study Analysis: GLP-1RAs on Weight Loss

Hello - If you aren't aware, under all my videos I have a 'Critique my Work' link so people can point out where I've made mistakes. Recently, someone (Dr. Mills) wrote in that one of the meta-analyses I covered in my GLP1RA study analysis had far more flaws in it than I presented. After a lengthy discussion with them, it seemed clear that the meta-analysis had more flaws in it than justifiable for a simple 'Amendment' under the video. As such, I've taken the video down.

Ultimately, the conclusion of the video likely stands (i.e. GLP1RAs cause weight loss), even in the face of this poor data, but it's still better to take down the video than keep it up with the assumption the data presented was high quality (because the end result isn't all that matters - learning how we get to that conclusion is also extremely valuable). Anyway, I'm thrilled to have had the opportunity to learn from an expert in meta-analysis like Dr. Mills, and expect to continue to improve to make sure I don't miss any other flaws in these types of studies.

Anyway, thank you to Dr. Kerry Mills for the corrections, and I hope you all have a great day.

Nic

8 months ago | [YT] | 1,249

Physionic

I get this question a lot - first off, I'm thankful anyone even gives a hoot what I have to say on the matter. Secondly, I'm working on it - I've pulled together 7 studies on the topic, and I'll do one more search to make sure I don't miss any others. It'll likely take me a few weeks to get through it all, but certainly expect me to cover it.

Looking forward to it,
Nic

8 months ago | [YT] | 1,108

Physionic

SEED OILS

I'm slowly turning my attention to covering how seed oils affect our health. As I'm a one man band and I have limited time, I'm asking you to choose the top two seed oils you've heard are the most destructive to our health. I'm happy to revisit the topic if people end up interested in wanting more, but for now, let's stick to the top two. I'm also working on other content that is not seed oil related (seedless content?).

I will be releasing another poll soon on the outcomes of interest (inflammation, heart disease, cancer, etc.) since they don't fit on this poll.

I added just these 4, because I can only poll 4 and these seem to get brought up a lot.

Thanks,
Nic

9 months ago | [YT] | 520

Physionic

Hi all - sourcing content ideas for the next few weeks of work. I have pulled these from the private, free Physionic Community and want to get a sense of which of these you'd be most interested in. I'll be doing more than these, but the top 2 or so from here I can go ahead and add to my short-list. Thanks.

10 months ago | [YT] | 581

Physionic

Xylitol is a common sugar substitute found in many keto friendly foods. Raise your hand if you want me to cover this new study?

Nevermind the fact that I can't see who doesn't raise their hand - if I see 500 billion hands raised, I'll get an impression that you guys are lukewarm on the topic.

11 months ago | [YT] | 2,504