The Academy by Psych Scene

Is It Really Treatment-Resistant Depression? Or Is It Just A Drug-Phenotype Mismatch?

Most label patients with depression as "treatment-resistant" after multiple unsuccessful SSRI or SNRI trials.

But what if the treatment isn't addressing the depression?

What if the drug's mechanism is simply mismatched to the disorder's unique phenotype?

Here’s what clinicians need to know about the monoamine approach to depression.

To learn more about the underlying mechanisms and limitations of monoamine-based antidepressants, click the link below and check out the full course inside The Academy:

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10 hours ago | [YT] | 3

The Academy by Psych Scene

Can Perinatal Sleep Disruption Contribute to Postpartum Psychosis (PPP)?

Perinatal sleep disruption is often dismissed as an expected consequence of early motherhood.

However, clinical and epidemiological data suggest that acute sleep loss and circadian rhythm disruption function as key precipitating and risk-modifying factors for postpartum psychosis in biologically vulnerable women.

Here’s how sleep disruption intersects with the neurobiology of PPP 👇🧵

To learn more about the nuanced neurobiological link between sleep and Postpartum Psychosis (PPP), click the link below and check out the full article on Psych Scene Hub:

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1 day ago | [YT] | 5

The Academy by Psych Scene

Why Don’t Most Trauma Survivors Develop Post-Traumatic Stress Disorder (PTSD)?

Epidemiological data indicates that 70% of the general population experiences at least one traumatic event and 30.5% experience four or more.

Yet, in contrast to these numbers, the lifetime prevalence of PTSD is only 5–10%.

This suggests that trauma exposure alone is not enough for PTSD pathogenesis.

Here's a comprehensive breakdown of why most trauma survivors don’t develop PTSD.

To learn more about the nuanced neurobiological mechanisms and clinical management strategies of Post-Traumatic Stress Disorder (PTSD) and C-PTSD, click the link in the comments below and check out the full interactive course on The Academy.

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2 days ago | [YT] | 11

The Academy by Psych Scene

Can Long-term Lithium Use Lead to Kidney Disorders Like Nephrogenic Diabetes Insipidus (NDI)?

Lithium has long been established as the first-line medication for Bipolar Disorder.

However, clinical data indicate that while it's known for its psychiatric efficacy, renal toxicity is frequent, with the risks of NDI appearing as early as 8 weeks into therapy due to lithium-induced rapid downregulation of water channels.

Here’s what clinicians need to know about the link between lithium and NDI.

To learn more about the pathophysiology and management of lithium-induced Nephrogenic Diabetes Insipidus (NDI), click the link below and check out the full article on Psych Scene Hub:

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3 days ago | [YT] | 9

The Academy by Psych Scene

Why Do Intrusive Memories in PTSD Feel So Real?

PTSD is not simply a psychological reaction to trauma; it is a stressor-induced alteration of one's neurocircuitry.

Clinical data shows that in PTSD, there is an overactivation of "Fear-On" circuits and a concurrent suppression of "Fear-Off" circuits in the amygdala, rendering the intrusive memories patients experience to feel as real as how they first went through it.

Here is a neurobiological breakdown of why intrusive memories in PTSD feel so real.

To learn more about the nuanced mechanisms of Post-Traumatic Stress Disorder, click the link in the comments below and check out the check out the course on The Academy:

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4 days ago | [YT] | 5

The Academy by Psych Scene

Sleep is a fundamental process governing cognition, emotional regulation, and neurobiological stability, yet its role in psychiatric disorders remains underrecognised.

“Sleep Disorders: Neuropsychiatric Approaches,” led by Dr Sanil Rege, provides a deep dive into the neurobiological link between sleep and mental health to improve diagnostic and treatment outcomes.

In this course, you’ll learn how to:

Explain the physiological processes and systems involved in sleep cycles and regulation.

Interpret the complex neurobiology and neurochemistry of sleep-wake regulation.

Determine how sleep-wake dysregulation influences mood, cognition, and symptom severity.

Assess structural and functional brain correlates in regions like the prefrontal cortex and limbic system.

Learn how specific psychotropic medications—from SSRIs to antipsychotics—alter sleep architecture.

Accreditation:

✅ 2 CPD hours (EA 1.5, RP 0.5)

✅ Self-accreditable with RANZCP

✅ Available for self-accreditation with RACGP

✅ 8 Modules | 39 Units | Course Completion Certificate

Start learning today by joining The Academy — click the link below:

6 days ago (edited) | [YT] | 6

The Academy by Psych Scene

How Do Antipsychotics Induce Metabolic Dysfunction?

Most assume that weight gain is the only side-effect of taking antipsychotics.

However, clinical data reveal that these agents also induce metabolic dysfunction, both directly and indirectly, by increasing blood glucose independent of adiposity and leading to uncontrolled lipolysis via adipose tissue dysregulation .

Here's a breakdown of how antipsychotics induce metabolic dysfunction and what clinicians can do in practice.

To learn more about antipsychotic-induced weight gain and metabolic dysfunction, click the link below and check out the full article on Psych Scene Hub:

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1 week ago | [YT] | 10

The Academy by Psych Scene

If Autism and ADHD Share Aetiology… Why Do They Look So Different Clinically?

Autism Spectrum Disorder (ASD) and ADHD overlap across multiple neurobiological domains including genetics, executive dysfunction, and dopaminergic signalling.

Yet in practice, they present very differently.

Why?

Here’s a breakdown of the key neurobiological differences between ASD and ADHD clinicians need to know.

For clinicians wanting deeper expertise in ADHD, comorbidity assessment, stimulant management, and formal ASD diagnostic frameworks our 6-course ADHD Curriculum covers this in depth, check the link in the comments:

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1 week ago | [YT] | 16

The Academy by Psych Scene

Can Post-Birth Hormonal Shifts Lead to Postpartum Psychosis (PPP)?

Postpartum Psychosis (PPP) is commonly misidentified as a severe form of postnatal depression.

However, clinical data suggest that hormonal shifts following delivery are associated with PPP as it forces a sudden, acute neurochemical withdrawal.

This withdrawal then induces a state of receptor hypersensitivity that destabilises the brain's reward and threat detection systems.

Here's a breakdown of how hormonal shifts contribute to PPP:

To learn more about the nuanced link between post-birth hormonal shifts and Postpartum Psychosis, click the link in the comments below and check out the full article on Psych Scene Hub.

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1 week ago | [YT] | 6

The Academy by Psych Scene

Psychiatry doesn’t slow down.

New research, updated guidelines, shifting frameworks, the field is constantly evolving. Keeping everything organised, current, and clinically useful in one place is almost impossible when you’re managing a full patient load and a personal life.

That’s where The Academy comes in.

Instead of scattered journals, fragmented CPD activities, and disconnected resources, you get one structured, clinician-focused platform.

Here’s what you get:

-150+ hours of expert-led, evidence-based content
-CME/CPD accreditation + free CPD Portfolio Tracker
-Flexible, on-demand video and audio learning
-Practical, clinician-ready frameworks
-Direct teaching from psychiatry experts
-Global peer collaboration
-Downloadable tools + instant certificates
-Full access for approximately AUD $1.64/day

Everything you need. One place.

Stay current. Stay confident. Future-proof your practice.

Join The Academy — click the link in the comments below:

1 week ago | [YT] | 4