Dermatology International Subspecialists (DERM.I.S), established in September 2023 and located in Angeles City, Pampanga, is a Philippine Dermatological Society–accredited clinic owned by Dr. Kara Melissa Culala and Dr. Jose Angelo Culala. headed by board-certified dermatologists, the clinic offers expertise in Medical Dermatology, Dermatopathology, Hair Specialty, Medical Aesthetic Dermatology, and Laser Treatments.

With a patient-centered approach, DERM.I.S provides personalized solutions for skin, hair, and nail conditions, ranging from complex skin medical cases to advanced aesthetic procedures, including hair restoration and transplantation. Guided by its core values of adaptability, radiance, and mission-driven care, the clinic is dedicated to building trust and satisfaction, positioning itself as a leading multi-subspecialty dermatology center in the Philippines.