Advancing Type 1 Diabetes Research Toward Curative Therapies: Lessons Learned and New Directions

Maintaining Identity: MAFB as a Guardian of the Adult Human Alpha-Cell - Katie Coate, PhD

Thousandfold Expansion Microscopy: Toward a Complete Molecular Map of Life -Helena Hu, PhD Candidate

TCR Gene Expression Predicts Future Type 1 Diabetes Risk Dependent on Immunogenetics -Michael Robben

Distinct Senescent Beta Cell Senotypes Differentially Drive Islet Aging and Dysfunction

Debate: Beta Cell Demise in Type 1 Diabetes

Seeing is Believing: Imaging the Pancreas in Type 1 Diabetes, Richard Benninger and Jason Bini

Beneficial Effects of Mesenchymal Stromal Cell-Derived Extracellular Vesicles on Beta-Cell Survival

Age Independent T1D Immune Subtypes Exhibit Distinct Progression Rates & Immunotherapeutic Responses

Role of Adaptive Immunity in Diabetes Due to RNA Editing Deficiency - Jonathan Belin, PhD Candidate

Flexible Electronic Implanted Cyborg Organoids Reveal Principles of Islet Cell Electrical Maturation

Understanding the Mechanisms of Human Beta Cell Replication & Maturation Using Insulinoma as a Model

AI-guided Analysis of Human Panc Islet Sociology Reveals Distinct Cell Compositional changes in T1D

How Close is T1D? Predict the Timing of the Metabolic Inflection Point Using ML & Survival Analysis

Thymic selection of multiple islet antigen-reactive HLA class II-restricted human T cell clones

Moving Small Molecule DYRK1A Inhibitors for Human Beta Cell Regeneration - Andrew Stewart, MD

When Beta Cell Specification Fails: A Knockout Village Reveals Lineage Rewiring in Human Islets

Structural Clues to HLA-B Mediated Type 1 Diabetes Risk - Ruby Sharma, PhD, Albert Einstein COM

Generation of Hypoimmunogenic Gastric Insulin-Secreting Organoids -Anna Ada Dattoli, PhD

A Surviving Beta Cell Subpopulation Enriched in Patients with Type 1 Diabetes - Max Spurrell

Biosensor Cell Array Reveals Temporal GABA Secretion Dynamics from Pancreatic Islets-Austin Stis PhD

Soluble LAG-3 Identifies an Early T cell Activation Window in self-reactivity Type 1 Diabetes

Genetic Association and Machine Learning Improve the Prediction of Type 1 Diabetes Risk

Reprogramming Innate & Adaptive Immunity for Durable Islet Allograft Survival - Haval Shirwan, PhD

ATG: Clinical History, Mechanistic Insights, & Future Directions for Type 1 Diabetes Treatment

Bioelectronic devices for immune protection and oxygenation of islets in vivo - Siddharth Krishnan

From Oxygen Limitation to Opportunity: Defining Hypoxia Resistance in Pancreatic Islets

Iron Deficiency Induces Maturation-dependent Loss of Beta Cells - Annelore Van Mulders

A Combinatorial Transcription Factor Screening Platform for Immune Cell Reprogramming-Filipe Pereira

Beta Cells Fight Back: Metabolic Reprogramming Shapes Immune Tolerance in Type 1 Diabetes-Kevin Bode

New Clinical Trials of Disease-modifying Therapy Should Focus on New-Onset & not Preclinical T1D

Quantitative V-gene-targeted T cell Receptor Sequencing as a Biomarker in Type 1 Diabetes

NKX6.1: Actionable Biomarker linked to Islet Function & Islet Transplantation Clinical Outcomes

Advancing Suspension Manufacturing of Islets In Vertical Wheel Bioreactors for Diabetes Therapy

Investigating Therapeutic Delivery to Beta-cells with Lipid Nanoparticles - Jacob Enriquez, PhD

Eledon T1D Trial: Immunomodulation with a CD40L antibody in combo with Transplanted Islet Cells

Long Non-coding RNAs (lncRNA) as a Novel Source of Beta Cell Autoantigens in Type 1 Diabetes

Can Islets Evade the Immune System Safely: Designing Tolerance without Compromising Host Defense

Linking Biological Rhythms to Beta Cell Maturation - Juan Alvarez, PhD, UPenn

Glucagon Secretion by Panc Alpha-cells Requires an Intact Tubulin-Cytoskeleton-Primary Cilium Axis

Saliva-based at-home GRS Testing for Scalable & Accessible T1D Screening - Yuta Matsuda, T1D Scout

Human Pancreas Integrated histopath through T1D progression - Verena van der Heide & Sara McArdle

the(sugar)science presents: the Diabdocs 2025 Cohort

High-throughput perturbation screens to decode human immune states-a sc cytokine dictionary of blood

Longitudinal monitoring of Type 1 Diabetes progression to disease onset - Lonnie Shea, PhD

Type 1 Diabetes Monitoring Panel - Challenges for Implementation and Engagement

Type 1 Diabetes Screening Panel: Moving from Research to Clinical Implementation

Panel: What would the earliest detection of Type 1 Diabetes look like?

Goal-oriented in Silicon Perturbations: Novel Counterfactual Deep Learning Framework in T1D

How the Human Immunome Project/IHM may inform Type 1 Diabetes - John Tsang, PhD, Yale

WAVE T1D Clinical Trial: Multicenter RCT Combo therapy in New-Onset Type 1 Diabetes

Multiscale Microenvironment Control in Stem Cell-Derived Pancreatic Progenitor Production

IL-17 Deficiency Protects NOD Mice from Diabetes through Altering Intestinal Antigen Presentation

Islet Cellularity in Health & Type 1 Diabetes: insights from deep tissue 3D imaging-Ulf Ahlgren, PhD

2025 Most Watched Highlights: Fast Tracking Stem Cell Derived Islets to the Clinic - What is Needed?

2025 Most Watched Highlights: Peter Thompson, PhD, & Jasmine Pipella, PhD Candidate

2025 Most Watched Highlights: Xin Chen, PhD

2025 Most Watched Highlights:Thomas Hill, PhD

2025 Most Watched Highlights: Ulf Hannelius, CEO

2025 Most Watched Highlights: Luc Teyton, MD PhD