Sign Gene is an Italian and American superhero film about Deaf superheroes starring Emilio Insolera, Carola Insolera, Ben Bahan, Hiroshi Vava, Humberto Insolera and Danny Gong. The story centres on a Deaf agent from New York City carrier of a powerful genetic mutation sent to Japan with his colleague to investigate the various intriguing crimes committed by Japanese Deaf mutants. The villains, like the agents, can create superhuman powers through Sign language.
The film makes several references to deaf history, culture and sign language linguistics. Six are the spoken languages in the film: English, Japanese, Italian, American Sign Language, Japanese Sign Language and Italian Sign Language.
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