METHODS – 80 Participants of #LMHRstudy fell within #MiHeart age range and were then matched 1:1 for age, gender, race, diabetes mellitus, hyperlipidemia, hypertension, and past smoking to asymptomatic subjects from the #MiHeart cohort.
PRIMARY ANALYSIS – High resolution heart scans (#CCTA) allowing for primary analysis of Total Plaque Score (TPS), Total Stenosis Score (TSS) and Segment Involvement Score (SIS)
RESULTS The matched mean age was 55.5 years, with mean #LDL cholesterol of 272 mg/dL (max LDL-C 591) mg/dl and mean 4.7 years duration on a ketogenic diet.
🚨 There was no significant difference in coronary plaque burden of #LMHRstudy (mean LDL-C 272) cohort as compared to #MiHeart controls (mean LDL 123 mg/dl); nb: pre-KETO LDL-C in KETO group was 122 mg/dl
🚨 There was no significant difference in CAC (median and IQR) [0 (0,56)] versus [1 (0, 49)], p = 0.520
🚨 No relationship of LDL-C elevations and plaque
⚠️ NOTE: This analysis is on baseline scans, we will have further data on the Keto-CTA longitudinal analysis in the coming months. And — as always — please continue to work with your doctor.
🙏🙏🙏 Special thanks to everyone who got us to this first publication milestone. 🙏🙏🙏
And a MASSIVE thanks to everyone who has contributed their money, time, and/or sharing to help us spread the word and make this research a reality!
(PS — this is unfortunately not Open Access as this wasn’t an option we had available for us — but the full manuscript will be published soon as a separate paper and *will* be open access)
Dave Feldman
🚨🚨🚨🚨🚨🚨🚨🚨
BREAKING: FIRST PUBLICATION NOW AVAILABLE —> www.metabolismjournal.com/article/S0026-0495(24)00…
KETO-CTA (#LMHRstudy) vs Control (#MiHeart)
-🙏Please Share! 🙏-
METHODS – 80 Participants of #LMHRstudy fell within #MiHeart age range and were then matched 1:1 for age, gender, race, diabetes mellitus, hyperlipidemia, hypertension, and past smoking to asymptomatic subjects from the #MiHeart cohort.
PRIMARY ANALYSIS – High resolution heart scans (#CCTA) allowing for primary analysis of Total Plaque Score (TPS), Total Stenosis Score (TSS) and Segment Involvement Score (SIS)
RESULTS
The matched mean age was 55.5 years, with mean #LDL cholesterol of 272 mg/dL (max LDL-C 591) mg/dl and mean 4.7 years duration on a ketogenic diet.
🚨 There was no significant difference in coronary plaque burden of #LMHRstudy (mean LDL-C 272) cohort as compared to #MiHeart controls (mean LDL 123 mg/dl); nb: pre-KETO LDL-C in KETO group was 122 mg/dl
🚨 There was no significant difference in CAC (median and IQR) [0 (0,56)] versus [1 (0, 49)], p = 0.520
🚨 No relationship of LDL-C elevations and plaque
⚠️ NOTE: This analysis is on baseline scans, we will have further data on the Keto-CTA longitudinal analysis in the coming months. And — as always — please continue to work with your doctor.
🙏🙏🙏 Special thanks to everyone who got us to this first publication milestone. 🙏🙏🙏
And a MASSIVE thanks to everyone who has contributed their money, time, and/or sharing to help us spread the word and make this research a reality!
(PS — this is unfortunately not Open Access as this wasn’t an option we had available for us — but the full manuscript will be published soon as a separate paper and *will* be open access)
1 year ago | [YT] | 210