As a LMHR (one year keto) that did have a cac score of 175 (formerly pre diabetic on SAD diet), I look forward to this info being mainstreamed. I look forward to the year 2 results (of the study) as well.
1 year ago (edited) | 10
Everything is off to a great start as I am a LMHR for the past year that has helped with my Epilepsy symptoms . Looking very much forward to the Longitudinal study results.
1 year ago | 5
CHAT GPT As of my last update in January 2022, I don't have specific information on a study that followed Lean Mass Hyper Responders (LMHRs) over a four-year period and found no increase in plaque despite high LDL cholesterol levels. However, if such a study has been conducted since then, it would represent significant findings in the field of lipidology and cardiovascular health.
1 year ago | 0
Is there a rough timeline on when the follow up scans will be published?
1 year ago | 0
Does anyone know if this comparison accounted for total body fat? LMHR's tend to be very healthy individuals in the classic sense.
1 year ago | 2
Unless your lowering the incidence of Apo B and impacting Pattern B that is shown to be causative in laying down of atherosclerotic plaques I’m still saying nope
1 year ago (edited) | 0
Who will be the last doctor still thinking LDL is the cause of heart disease? (And that statins are safe and effective) Who will be the last dentist still using mercury fillings? (and thinking mercury is safe and effective.)
1 year ago | 5
I unfortunately qualify as hiper risponder not LMHR because my TG are like 100. Nevertheless I'm very excited about the work that you guys are doing. Can't wait till you publish the results of the second angiography of the coronary arteries!
1 year ago | 0
Looking for research on prolonged fasting and reduction of CAC. 7days to 40 days water fast
1 year ago | 0
Am I understanding that the ketogenic diet didn't reduce the plaque, so people on a ketogenic diet would have a similar risk of heart disease?
1 year ago | 0
Now do cohort of obese middle age meat eaters. Not skinny young females Lolol.
1 year ago | 0
Dave Feldman
🚨🚨🚨🚨🚨🚨🚨🚨
BREAKING: FIRST PUBLICATION NOW AVAILABLE —> www.metabolismjournal.com/article/S0026-0495(24)00…
KETO-CTA (#LMHRstudy) vs Control (#MiHeart)
-🙏Please Share! 🙏-
METHODS – 80 Participants of #LMHRstudy fell within #MiHeart age range and were then matched 1:1 for age, gender, race, diabetes mellitus, hyperlipidemia, hypertension, and past smoking to asymptomatic subjects from the #MiHeart cohort.
PRIMARY ANALYSIS – High resolution heart scans (#CCTA) allowing for primary analysis of Total Plaque Score (TPS), Total Stenosis Score (TSS) and Segment Involvement Score (SIS)
RESULTS
The matched mean age was 55.5 years, with mean #LDL cholesterol of 272 mg/dL (max LDL-C 591) mg/dl and mean 4.7 years duration on a ketogenic diet.
🚨 There was no significant difference in coronary plaque burden of #LMHRstudy (mean LDL-C 272) cohort as compared to #MiHeart controls (mean LDL 123 mg/dl); nb: pre-KETO LDL-C in KETO group was 122 mg/dl
🚨 There was no significant difference in CAC (median and IQR) [0 (0,56)] versus [1 (0, 49)], p = 0.520
🚨 No relationship of LDL-C elevations and plaque
⚠️ NOTE: This analysis is on baseline scans, we will have further data on the Keto-CTA longitudinal analysis in the coming months. And — as always — please continue to work with your doctor.
🙏🙏🙏 Special thanks to everyone who got us to this first publication milestone. 🙏🙏🙏
And a MASSIVE thanks to everyone who has contributed their money, time, and/or sharing to help us spread the word and make this research a reality!
(PS — this is unfortunately not Open Access as this wasn’t an option we had available for us — but the full manuscript will be published soon as a separate paper and *will* be open access)
1 year ago | [YT] | 210