Nice to see it confirmed with brain flow and insulin resistance. I’m sure Doritos scientists well aware
1 week ago | 2
i thought BBC already shown that, the brain gets rewire completely, before and after scan.
1 week ago | 1
Really appreciate the work you are putting in my man! I am 25 years old and I’ve spent close to 2 decades of my life prioritizing longevity. It’s truly inspiring to see someone cut through this industry’s BS by such concise and accurate means. If I wasn’t a broke GenZ you’d 100% be the first Newsletter I would feel offers enough value to subscribe to. Take care and keep up the good fight sir!
1 week ago | 6
Skeptical of the long-term results of this. Since the brain rewires constantly through its entire life... I mean, are you alleging that once this "scar" is formed you are now an addict, or likely an addict? I'd like to see them check the brain again in a few months. I bet it returns to near baseline. Anyhow, people can and do overcome all sorts of "wired" addictions. People naturally give up heroine after decades of use, often on their own. Not saying this isn't interesting, but it is far from a silver bullet. You need to prove that this "scar" results in a life-long obsession with binge eating while at the same time, separating out this "scar" with other behaviors and drugs that mimic euphoria. People generally repeat behaviors they enjoy and so, how is this unique to junk food only? It may sound like I am defending junk food - I am not, but that is far different from doom and gloom of someone who once had an unhealthy diet. I am still reading the study. Help me understand why follow-up #1 didn't measure the same brain areas as follow-up #2? Wouldn't it make sense to see if levels started to normalize? They should have measured ALL 4 areas of the brain, so that we could see the changes on the second follow-up. Lastly, there should be been another follow-up further out.
1 week ago (edited) | 4
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1 week ago | 1
Nick Norwitz
A Junk Food Binge Can Scar the Brain.
Link: staycuriousmetabolism.substack.com/p/this-study-ch…
I just read a controlled human trial in Nature Metabolism that proves a junk food binge does something far worse than add a few inches to your waistline.
It leaves a "metabolic scar" on your brain.
Researchers took 29 healthy, young men and split them into two groups. One group consumed a "high-calorie" diet loaded with chips, brownies, and junk food for just five days.
Most people focus on the scale, but in this study, the high-calorie group saw no significant increase in body weight.
However, inside their bodies, the story was different. Liver fat spiked by a striking 64% (from 1.55% to 2.54%) and brain blood flow decreased significantly to the hippocampus and fusiform gyrus.
These brain regions are essential for memory, learning, and self-control. They are the parts of your brain that "put the brakes" on impulsive eating. When blood flow drops, those regions go quiet.
Simultaneously, the brain developed specific insulin resistance. It lost the signal to "stop eating."
The binge rewired the brain to crave more while physically weakening the willpower to resist. It’s a vicious biological cycle.
Click the link above for the full deep dive.
#MetabolicHealth #Neuroscience #NutritionScience #PublicHealth #InsulinResistance #NewResearch #BrainHealth
1 week ago | [YT] | 389