Highly Compelling

According to Geneticist David Reich these models are WRONG. They are very "low probability" only 5%, and are "increasingly implausible". He is saying that Neanderthals may have up to 70% modern human DNA, rather than there being an introgression event.

The most commonly reported scenario is the modern human mtDNA replaced Neanderthal mtDNA (late Introgression hypothesis) but a second scenario is that some Neanderthals always had a modern human mtDNA (Deep structure hypothesis).

The HST (Hohlenstein-Stadel) sample from southern Germany dates to 125,000 years ago and has a deeply divergent mtDNA that is closer to modern humans but also different than Neanderthals....

The Scladina Neanderthal lived around 120,000 years ago but had the the more common modern human mtDNA. So it is very strange that these two lived very close in time and place but had different mtDNA.

4 weeks ago (edited) | [YT] | 135



@kim1628

The only thing I can think of is this. Sima de los Huesos were 430K year old proto-Neanderthal with Denisovan mtDNA. HST lineage can be traced back to 270K years ago, and they had human mtDNA. The LCA went to Asia and evolved into Denisovan. The ones that stayed in Europe evolved into Neanderthal, and further intermixed with archaic Homo sapien.

4 weeks ago | 7

@kim1628

I believe the Vindija Neanderthal had Neanderthal mtDNA. As you know, Vindija Neanderthal is the one we extracted full genome of Neanderthal from, and it was dated 44,000 year ago, supposedly before the arrival of Homo sapien in Europe. There are many different explanation to this.

4 weeks ago | 6

@mladenmatosevic4591

We need way more specimens to find and analyze before we can truly figure this.

4 weeks ago | 7  

@emjay2fly

I love this because I always hate the neat clean branches of groups splitting off. We dont see this in current modern human populations so why would it be any different in the middle Pleistocene. I think neanderthals were fundamentally created through gene flow of multiple sources I feel the same about denisovan and modern humans.

4 weeks ago | 1  

@kim1628

This had to be the continuation research from the Sima de los Huesos. I remember J. Klause of Max Plank Institute wanted to get the genetic material from HST which is a Neanderthal from ancient lineage. Since Neanderthal’s Denisovan mtDNA was eventually replaced, HST would be a good starting point. But I don’t think they expected this result.

4 weeks ago | 5

@solitudesilentgroove

Trying to make sense of this and sorry for being stupid, but I heard it was the y chromosome in the Neanderthals that didn't propagate. So male hybrids were infertile but not females. How does that make sense with what you just posted?

4 weeks ago | 7  

@JB-1138

Capt. Picard: "In plain English Mr. Data -"

4 weeks ago | 1  

@JB-1138

There are lots of people who still look very neanderthal.

4 weeks ago | 2

@netdragon256

So neanderthals never had mtDNA but always had human mtDNA? That statement is self-contradictory. Please proofread, people. It doesn't matter that we know you meant "neanderthal mtDNA"

4 weeks ago | 2

@DAlienzombie

It was speculated, that those populations - as they are regional close to older H. Erectus syted findings - had a differrent influence of ancestry lineages, and propably a special social status and traditions.

4 weeks ago | 2

@kim1628

This was the previous article that lead to this research: https://www.nytimes.com/2017/07/04/science/neanderthals-dna-homo-sapiens-human-evolution.html

4 weeks ago | 1

@vitolucania432

You know that you are an anatomically modern human and not a Neanderthal right? You speak about them as if they are the ancestors!

4 weeks ago | 2