She actually did have “high” ldl cholesterol. Nick norwitz said he had to dig all the literature on her to find it because they really tried to omit this from the findings. Doesn’t fit the mainstream narrative I guess.
1 day ago | 0
This looks like AI wrote a descriptive post to explain her LDL, hsCRP and a couple of other snapshots in time.
3 days ago | 0
Ben Greenfield Life
This woman lived to 117: here’s what her genes and lifestyle tell us about longevity - www.nature.com/articles/d41586-025-03112-6
Want to know the quick details? Keep reading.
Scientists studied Maria Branyas, the world’s oldest person, using multi-omics (genomics, proteomics, etc.) to map her biology. Spoiler: It’s a mix of good genes and body hacks fighting aging. 🧬👵
Methods: They analyzed blood samples for DNA, proteins, metabolism, gut bacteria, and more—without invasive tests. Compared her to typical 100-year-olds and younger folks. This is the deepest dive into a supercentenarian yet. 🔬
Aging signs were there: Super short telomeres (like frayed chromosome ends), mutations in blood cells (clonal hematopoiesis), and more age-related B cells in her immune system. Her body showed extreme age—but handled it like a boss. ⏳
Protective genes: Rare variants that shield the heart and brain from damage. Think built-in armor against heart disease and neurodegeneration. These aren’t common, but they might explain why she dodged major illnesses. ❤️🧠
Metabolism win: Active lipid (fat) processing kept things balanced. No high cholesterol or diabetes markers—her body efficiently managed energy, avoiding common old-age pitfalls. ⚡
Low inflammation: Unlike most elderly, her inflammation levels were chill, reducing wear and tear on organs. Plus, an efficient immune response that fought threats without overreacting. 🛡️
Gut health bonus: A “rejuvenated” microbiome full of beneficial bacteria like bifidobacteria, similar to younger people. This supports digestion, immunity, and overall vibe - and she ate Mediterranean-style foods: olive oil, fish, and 3 servings of plain yogurt daily. 🦠
Epigenetic youth: Her “epigenetic clocks” (DNA markers of biological age) ticked slower—she was epigenetically younger than her 117 years. This deceleration might be key to her extra decades. 🕰️
Big picture: No magic pill, but this shows longevity comes from genes, low inflammation, strong immunity, and a young-like biology. Could inspire treatments for aging diseases.
3 days ago | [YT] | 24