Dr Matt Kaeberlein

Optispan is a vision for what health should be.

The typical person gives up 10-20 years of quality life in exchange for disability, frailty, and early death. We call this "the lost decade". Time that should be spent with loved ones doing the activities you enjoy are instead spent suffering from multiple diseases and taking a cabinet full of medications that probably do as much harm as good.

We believe that the current practice of medicine is disease care, not health care. We believe that everyone can get closer to their own optimal healthspan.

Join us on a journey of discovery as we explore the science of longevity and optimal healthspan ("Optispan"). The journey is the reward.

We hope you find this content valuable, join by subscribing to the channel, and come back often. More importantly, we hope that you apply what you learn here to recover your lost decade, and perhaps much more.



Dr Matt Kaeberlein

Where do you stand on NAD+ boosters (NMN/NR)?

3 days ago | [YT] | 7

Dr Matt Kaeberlein

They flipped the food pyramid upside down, called past efforts a "failure," and sparked a lot of debate.

On the latest Optispan Podcast, Matt does a full forensic breakdown, reading every single word, to separate the science from the politics and give you the clear takeaways.

Episode live on the channel!

1 week ago | [YT] | 26

Dr Matt Kaeberlein

Old guidelines said: "≤1 drink/day (women), ≤2 drinks/day (men)."
New guidelines say: "Consume less alcohol for better health."
Which approach is more helpful?

1 week ago | [YT] | 7

Dr Matt Kaeberlein

The 2025-2030 Dietary Guidelines are out with a flipped food pyramid and a big "eat real food" message. At first glance, what's your take?

1 week ago | [YT] | 5

Dr Matt Kaeberlein

Do you avoid non-stick (Teflon/PFAS) pans?

2 weeks ago | [YT] | 7

Dr Matt Kaeberlein

Season 3 is HERE 🎙️

New Year’s stories from Times Square, Anderson Cooper moments, and a quick breakdown of Peter Attia’s latest 60 Minutes takes.

Episode’s live on the channel. Go check it out.🔥

2 weeks ago | [YT] | 12

Dr Matt Kaeberlein

Do you take a daily multivitamin?

3 weeks ago | [YT] | 10

Dr Matt Kaeberlein

This is why frequent testing is important

3 weeks ago | [YT] | 18

Dr Matt Kaeberlein

It’s important to know your baseline.

For example, if someone usually has a hemoglobin of 17 and it drops to 13, that’s huge, even if it’s still “normal.”

Frequent testing shows the trend, not just a single number, so we can make smarter health decisions with the doctor.

3 weeks ago | [YT] | 21

Dr Matt Kaeberlein

Being 80 but having the hormones of a 25-year-old didn’t save her from a stroke.

3 weeks ago | [YT] | 28