Dr Matt Kaeberlein

Optispan is a vision for what health should be.

The typical person gives up 10-20 years of quality life in exchange for disability, frailty, and early death. We call this "the lost decade". Time that should be spent with loved ones doing the activities you enjoy are instead spent suffering from multiple diseases and taking a cabinet full of medications that probably do as much harm as good.

We believe that the current practice of medicine is disease care, not health care. We believe that everyone can get closer to their own optimal healthspan.

Join us on a journey of discovery as we explore the science of longevity and optimal healthspan ("Optispan"). The journey is the reward.

We hope you find this content valuable, join by subscribing to the channel, and come back often. More importantly, we hope that you apply what you learn here to recover your lost decade, and perhaps much more.



Dr Matt Kaeberlein

To go viral, influencers often share claims with no scientific backing.

22 hours ago | [YT] | 11

Dr Matt Kaeberlein

Biological age tests use single markers, like testosterone, to estimate your ‘age.’

My TRT raised testosterone above 800, which the test interpreted as super young, but that doesn’t actually reverse decades of aging.

Improving health isn’t the same as reversing age.

1 day ago | [YT] | 19

Dr Matt Kaeberlein

One test said I’m 40. Another said I’m basically 70. So, what’s my real biological age?

2 days ago | [YT] | 16

Dr Matt Kaeberlein

Connection is one of the four pillars of our health, so make sure to take time to nourish the social networks that support you this holiday season! This is just one example of the insights you can receive through our partnership with Help Texts, which you can sign up for through the link in our bio, or at longevitytexts.com


#connect #friends #family

3 days ago | [YT] | 20

Dr Matt Kaeberlein

Do you think epigenetic "ageing clocks" will ever be reliable clinical tools?

3 days ago | [YT] | 3

Dr Matt Kaeberlein

Before TRT, my “biological age” came in at 69.8 years.

VO₂ max said 40.5 years. Hippocampal volume and kidney function would each give different results.

They can’t all be right.

That’s because none of these numbers measure true biological age.

3 days ago | [YT] | 23

Dr Matt Kaeberlein

Ever heard of the "Horvath Clock"? Where did you hear it first?

4 days ago | [YT] | 5

Dr Matt Kaeberlein

It’s a perfect example of how false information can spread faster than actual science

4 days ago | [YT] | 25

Dr Matt Kaeberlein

Precision matters in science. The Horvath Clock, created in 2013 by my friend Steve Horvath, estimates biological age from DNA methylation.

5 days ago | [YT] | 28

Dr Matt Kaeberlein

If a doctor recommended a direct-to-consumer "biological age" test to you, what would you do?

5 days ago | [YT] | 6