PharmaMedics
"Welcome to PharmaMedics! We create simple, easy-to-understand Pharmacy+ medical related educational videos with images and 3D visuals for better learning and clear understanding."
"Welcome to PharmaMedics! We create simple, easy-to-understand Pharmacy+ medical related educational videos with images and 3D visuals for better learning and clear understanding."
PharmaMedics
1 week ago | [YT] | 0
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PharmaMedics
CLASS: Triptans
Drug Class: Selective 5-HT₁B/₁D receptor agonists
Derived From: 5-Hydroxytryptamine (Serotonin)
Purpose: Abortive treatment for migraines and cluster headaches
Examples: Sumatriptan, Rizatriptan, Zolmitriptan
🧠 MECHANISM OF ACTION
Triptans relieve migraines by acting on serotonin receptors in the brain:
Vasoconstriction
Stimulate 5-HT₁B receptors on cranial blood vessels
Reverse migraine-associated vasodilation
Neurotransmitter Inhibition
Activate 5-HT₁D receptors on trigeminal nerve endings
Suppress release of CGRP, substance P, and neurokinin A
Pain Signal Modulation
Reduce transmission of pain signals in the brainstem
💊 USES
Acute Migraine Attacks
Cluster Headaches
Menstrual Migraine Relief
⚠️ SIDE EFFECTS
Chest Pressure or Tightness
Dizziness or Fatigue
Tingling or Numbness (Paresthesia)
🚫 CONTRAINDICATIONS
Avoid Triptans in patients with:
Coronary Artery Disease or history of heart attack
Uncontrolled Hypertension
Stroke or Transient Ischemic Attack (TIA)
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1 year ago | [YT] | 0
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