Headache / Medical research (Faraidoon, MD, PhD)

Chronic migraine can take over so much of a person’s life, so it is always encouraging to see strong new evidence that helps guide prevention more clearly.
I am very happy to share this new paper on pharmacologic prophylaxis for chronic migraine. This systematic review of 43 randomised controlled trials including 14,725 participants found that several calcitonin gene-related peptide targeted treatments, including eptinezumab, erenumab, fremanezumab, galcanezumab, and atogepant, can reduce monthly migraine headache days by around 2 compared with placebo. Botulinum toxin may also help, although the certainty of evidence was lower, while older treatments such as topiramate, valproate, and propranolol had limited lower-quality evidence.
This was also a very nice collaboration with a great team at the Michael G. DeGroote Institute for Pain Research and Care, McMaster University, Hamilton, Ontario, Canada, and it has already resulted in several nice papers. I am grateful to have worked with such a thoughtful and productive group.
Paper: www.acpjournals.org/doi/10.7326/ANNALS-25-02221
Summary for patients: www.acpjournals.org/.../10.7326/ANNALS-25-02221-PS
Summary video: www.acpjournals.org/.../10.7326/ANNALS-26-01204-VS
#ChronicMigraine #Migraine #HeadacheResearch #Neurology #SystematicReview #CGRP #PainResearch #EvidenceBasedMedicine

1 week ago | [YT] | 0

Headache / Medical research (Faraidoon, MD, PhD)

I recently had the opportunity to present my work on cluster headache (Cluster Headache gaps and future trials), including findings from our 2026 study on patient perspectives in Australia and an overview of our upcoming PEACE trial exploring psilocybin as a potential treatment.

It was a great session hosted by the Australia New Zealand Cluster Headache Support, with strong engagement from the community and meaningful discussions around lived experience, unmet needs, and future directions in research.

This work is especially important because cluster headache remains one of the most severe and under-recognised conditions, and patients continue to seek better, more effective treatment options.

I truly appreciate the opportunity to share this work and connect with such an engaged and passionate community.

pubmed.ncbi.nlm.nih.gov/41562498/

1 month ago | [YT] | 0

Headache / Medical research (Faraidoon, MD, PhD)

Photo taken after receiving too many emails 🤣🤣🤣🤣🤣🤣🤣
(Just for fun!)

1 year ago | [YT] | 2

Headache / Medical research (Faraidoon, MD, PhD)

👇👇👇👇👇

1 year ago | [YT] | 0

Headache / Medical research (Faraidoon, MD, PhD)

Do you want to know how to check if a journal is a good journal?

In this post, I talk about it in a very short video.

#journal #research
#headache #migraine

1 year ago | [YT] | 0

Headache / Medical research (Faraidoon, MD, PhD)

How to check the impact of your research?

1 year ago | [YT] | 1

Headache / Medical research (Faraidoon, MD, PhD)

How to promote your paper after publication?

1 year ago | [YT] | 1

Headache / Medical research (Faraidoon, MD, PhD)

Well done ‪@VitalityVortexChannel‬

2 years ago | [YT] | 1

Headache / Medical research (Faraidoon, MD, PhD)

Which topic do you want me to make a video about first?

2 years ago | [YT] | 0