The Breakthrough Prize is the world’s largest scientific award, given for major advances in Fundamental Physics, Life Sciences and Mathematics. Laureates receive $3 million and are honored at a globally broadcast award ceremony. The Breakthrough Prizes were founded by Sergey Brin, Priscilla Chan and Mark Zuckerberg, Yuri and Julia Milner, and Anne Wojcicki. breakthroughprize.org.

The Breakthrough Junior Challenge is a competition for students, ages 13-18, to share their passion for math and science with the world! breakthroughjuniorchallenge.org.

The Breakthrough Initiatives seek scientific evidence of life in the Universe. The first initiative is Breakthrough Listen, the most comprehensive, intensive and sensitive search ever undertaken for artificial signals. The Breakthrough Initiatives were founded by Yuri and Julia Milner as part of their Giving Pledge to support scientific programs and the communication of scientific ideas. breakthroughinitiatives.org.


Breakthrough

Premiering today – Journey to the Heart of Matter: CERN Director-General and Special Breakthrough Prize winner Fabiola Gianotti gives an overview of the cutting-edge work by 4 experimental teams at the LHC that won this year’s Breakthrough Prize in Fundamental Physics.

4 months ago | [YT] | 6

Breakthrough

Premiering today – Hidden Triggers: 2025 Breakthrough Prize winners Alberto Ascherio and Stephen Hauser explain their discoveries of the causes and mechanisms of multiple sclerosis.

4 months ago (edited) | [YT] | 4

Breakthrough

Premiering today – Life in the Balance: 2025 Breakthrough Prize winners Lotte Bjerre Knudsen and Jens Juul Holst tell the story of GLP-1 and how it has revolutionized the treatment of diabetes and obesity.

4 months ago | [YT] | 5

Breakthrough

Premiering today – The Bridge: 2025 Breakthrough Prize winner Dennis Gaitsgory describes his thirty-year love affair with the Geometric Langlands conjecture.

5 months ago | [YT] | 3

Breakthrough

Premiering today – The Gene Editor: 2025 Breakthrough Prize winner David Liu introduces base editing and prime editing, the transformative technologies that could repair almost any genetic mutation.

5 months ago | [YT] | 1

Breakthrough

MrBeast joined Julia Milner to announce Jasmine Eyal as the winner of the Breakthrough Junior Challenge, a global science video competition. Eyal said, “We should celebrate the brilliant scientists here today, not only for their incredible achievements but for the young minds they’ll inspire.”

6 months ago | [YT] | 3

Breakthrough

Jeff Bezos and Yuri Milner award the 2025 Breakthrough Prize in Fundamental Physics to thousands of researchers from more than 70 countries who contributed to four experimental collaborations at CERN’s Large Hadron Collider. Bezos described their pursuit for new knowledge as a “a quest, driven by pure curiosity” that “has also improved all of our lives.”

6 months ago | [YT] | 6

Breakthrough

James Corden opened the Breakthrough Prize ceremony toasting the event as “the one night Hollywood and Science come together,” calling out celebrities in the room, including Jeremy Strong and Margot Robbie, and performing a rousing Gilbert-and-Sullivan-style tribute to this year’s laureates.

6 months ago | [YT] | 2

Breakthrough

Watch Sia close the 2025 Breakthrough Prize ceremony with an inspiring rendition of “Unstoppable” as all prize laureates return to the stage to a standing ovation.
https://youtu.be/pqZcyznpHq0

6 months ago | [YT] | 17

Breakthrough

Breakthrough Junior Challenge winner Sia Godika is presented by Jessica Chasten and Julia Milner at the Breakthrough Prize ceremony.

1 year ago | [YT] | 4